Mass Spectrometry in Drug Metabolism and Pharmacokinetics

This timely reference discusses mass spectrometry in drug metabolism and pharmacokinetic studies. Advanced mass spectrometry techniques to support your drug discovery and development research Inside this book are a host of practical tools and techniques that enable you to fully leverage the capabilities of mass spectrometry in order to get the most out of drug metabolism and pharmacokinetics studies. You'll learn the latest applications for determining how a drug is absorbed, distributed, metabolized, and excreted by the body. Logically organized, Mass Spectrometry in Drug Metabolism and Pharmacokinetics starts off with an overview of the role of mass spectrometry in drug discovery and development. It then shows you how to perform routine applications before introducing you to sophisticated tools and techniques for solving complex drug metabolism and pharmacokinetics problems. Throughout the book, the main focus is on the use of LC-MS and MALDI-MS. Each chapter has been written by one or more leading experts who share their own first-hand laboratory experience. You'll gain a wealth of tips for performing successful analyses as well as avoiding common pitfalls. Moreover, the book is packed with features that help you grasp new concepts quickly and put your knowledge into practice, including: Figures and illustrations to help you understand how to perform specific techniques and applications Charts and tables that serve as quick summaries and reference guides Coverage of the latest tested-and-proven techniques References leading to the primary literature in the field Carefully edited to ensure thoroughness and a uniform standard of quality, this book is sure to help you advance your own important drug research efforts. This timely reference discusses mass spectrometry…