Principles of Hormone Replenishment Therapy for Longevity and Living Younger

The Clinical Reference Prescribers Have NeededEvery week, patients arrive asking about hormones - bioidentical estrogen, testosterone optimization, progesterone, DHEA. Most clinicians received minimal formal training in hormone therapy beyond residency basics. The FDA's July 2025 expert panel found that fewer than one in three U.S. residency programs carry standardized menopause curriculum. Evidence has moved. Guidelines have shifted. Patient expectations have not waited.Nathaniel Alder, MD brings 14 years of clinical experience in hormone therapy and longevity medicine to a subject where most available resources are either outdated textbooks or consumer wellness guides. Principles of Hormone Replenishment Therapy for Longevity and Living Younger is the clinical manual written by a prescriber, for prescribers - grounded in the post-WHI evidence re-evaluation and the current regulatory landscape, including the FDA's July 2025 advisory panel findings on menopausal hormone therapy.What This Manual Provides- Patient selection criteria and risk stratification frameworks for initiating hormone therapy across all major sex hormones- Dosing protocols and titration guidance for estrogen, progesterone, testosterone, and DHEA - including bioidentical and conventional pharmaceutical options- Laboratory evaluation and interpretation - what to measure, when, and what the results mean clinically- Monitoring schedules and safety parameters across all treatment phases- Evidence-based comparison of bioidentical versus conventional hormone options, including compounding considerations- Long-term outcome data: cardiovascular, cognitive, bone density, and metabolic effects- Clinical integration of hormone therapy within a longevity medicine framework for the aging female and male patientWho…