Pharmacogenomics: Foundations, Competencies, and the Pharmacists' Patient Care Process

Pharmacogenomics: Foundations, Competencies, and the Pharmacists’ Patient Care Process provides a basic and clinical foundation for the application of drug-gene interactions in clinical therapeutics. As the field of PGx advances, there is a need for a pharmacy-based, directed resource that can be a reference for practicing pharmacists and student pharmacists. Specific information is presented through “PGx Pearls.” Each of the 17 cases are presented in the context of the PPCP, with “Competency Connections” related to genetics and genomics. Each of the 29 chapters providescontent and objective related questions with the answers provided. Two appendices are included. KEY FEATURES: Connects the clinical application with basic foundational principles of pharmacogenomics Includes pharmacogenomics case studies across therapeutic areas PPCP-focused content that reinforces the pharmacists’ role in pharmacogenomics Ideal for adoption in courses teaching pharmacogenomics and pharmacogenetics Chapter 1. Foundations of Pharmacogenomics Chapter 2. Pharmacogenomics: Drug Exposure and Response Chapter 3. Pharmacists Competencies in Genetics/Genomics Chapter 4. Information Resources for Pharmacogenomics Chapter 5. Implementation of Pharmacogenomics across Practice Settings Chapter 6. The Pharmacists’ Patient Care Process (PPCP) Chapter 7. Cardiology: Clopidogrel/CYP2C19 Case Chapter 8. Cardiology: Simvastatin/SLCO1B1 Case Chapter 9. Cardiology: Warfarin/CYP2C9, VKORC1, CYP4F2 Case Chapter 10. Endocrinology: Glipizide/G6PD Case Chapter 11. Immunology: Tacrolimus/CYP3A5 Case Chapter 12. Infectious Diseases: Abacavir/HLA-B Case Chapter 13. Infectious Diseases: Atazanavir/UGT1A1 Case Chapter 14. Infectious Diseases: Voriconazole/CYP2C19 Case Chapter 15. Neurology: Carbamazepine/HLA-A, HLA-B…